Main Street Station
Main Street Station may refer to:
- Main Street Station (Richmond), a railroad station Richmond, Virginia
- Main Street (TTC), a subway stop Toronto, Ontario
- Flushing–Main Street (IRT Flushing Line), a subways stop in Flushing, New York
- Evanston Main Street (Metra), a commuter rail stop in Evanston, Illinois
- Main Street Station Hotel and Casino and Brewery, Las Vegas, Nevada
- Main Street – Science World Station, a Vancouver SkyTrain station formerly known as Main Street Station